A common story told in the Paducah area is that William Clark, of the Lewis and Clark fame, named Paducah for a Chickasaw chieftain called Chief Paduke, but this is incorrect. Clark was actually referring to a tribe he learned about during his travels exploring the west.
In a letter to his son on April 27, 1827, Clark wrote:
“I expect to go to the mouth of the Tennessee River, and be absent about two weeks. I have laid out a town there and intend to sell some lots in it, the name is Paducah, one of the largest Indian nations known in this country, and now almost forgotten.”